On computer-aided fractal analysis of growth processes at tumor-stroma border
Volume 109 / 2016
Banach Center Publications 109 (2016), 167-182
MSC: Primary 68-XX; Secondary 68T45.
DOI: 10.4064/bc109-0-11
Abstract
In the characterization of carcinomas, an important criterion is the shape of the tumor-stroma frontier and, in particular, its fractal dimension. The definition and identification of this frontier is not trivial. For the same image, the known segmentation algorithms often produce frontiers with very different fractal dimensions making this type of analysis irrelevant. We introduce a new approach to frontier analysis by redefining the tumor-stroma frontier in order to overcome this problem.